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Sigma-Aldrich

3-Aminoquinoline

98%

Synonym(s):

3-AQ, 3-Quinolinamine

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About This Item

Empirical Formula (Hill Notation):
C9H8N2
CAS Number:
580-17-6
Molecular Weight:
144.17
Beilstein/REAXYS Number:
113317
EC Number:
209-455-1
MDL number:
MFCD00006772
UNSPSC Code:
12352100
PubChem Substance ID:
24853890
NACRES:
NA.22

assay

98%

form

solid

mp

91-92 °C (lit.)

SMILES string

Nc1cnc2ccccc2c1

InChI

1S/C9H8N2/c10-8-5-7-3-1-2-4-9(7)11-6-8/h1-6H,10H2

InChI key

SVNCRRZKBNSMIV-UHFFFAOYSA-N

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Application

3-Aminoquinoline was used:
  • in liquid matrix for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) for glycopeptides, carbohydrates and phosphopeptides
  • in liquid matrix during novel glycan-labeling method for quantitative profiling of N-glycan by MALDI-MS analysis
  • as derivatizing reagent for MALDI-MS analysis of oligosachharides

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yuzo Yamazaki et al.
Journal of the American Society for Mass Spectrometry, 31(6), 1180-1188 (2020-04-17)
Polyrotaxane (PR) is a necklace-like supramolecule composed of cyclic components, such as cyclodextrin (CD), and a threading polymer capped with bulky end groups. PR exhibits peculiar mechanical properties attributed to the intermolecular cross-links with CD. Various CD molecules threaded on
Yuko Fukuyama et al.
Analytical chemistry, 86(4), 1937-1942 (2014-02-07)
Glycosylation and phosphorylation are important post-translational modifications in biological processes and biomarker research. The difficulty in analyzing these modifications is mainly their low abundance and dissociation of labile regions such as sialic acids or phosphate groups. One solution in matrix-assisted
Hayden Wilkinson et al.
Journal of proteome research, 19(10), 3890-3905 (2020-09-08)
Glycosylation is crucial in cellular metabolism and survival. Of interest is the role of N-linked and O-linked glycans in disease states. Robust analytical methods must be defined to identify suitable glycan biomarkers and glyco-therapeutics. Fortunately, in N-glycan analysis, a universal
Qiwei Zhang et al.
Mass spectrometry reviews, 37(5), 652-680 (2017-12-12)
Sialic acids are a family of structurally unique and negatively charged nine-carbon sugars, normally found at the terminal positions of glycan chains on glycoproteins and glycolipids. The glycosylation of proteins is a universal post-translational modification in eukaryotic species and regulates
Clara Granzotto et al.
Analytical chemistry, 89(5), 3059-3068 (2017-02-15)
This paper reports an improved method for the identification of Acacia gum in cultural heritage samples using matrix assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS) after enzymatic digestion of the polysaccharide component. The analytical strategy was optimized using a
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