The inhibition of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1) with three phenols was investigated. Phenol was an effective CA I-IV, IX, XII and XIV inhibitor (K(I)s of 2.7-11.5 microM) and a less effective one against the other isoforms, CA
A convenient synthesis of 4-alkoxy-and 4-hydroxy-2, 6-difluoroanilines.
The solubilities of several cobalt(III) chelates (CoL3) with in supercritical carbon dioxide (SC-CO2) were investigated in the presence of fluorine- and trifluoromethyl-substituted phenols (PhOH) using UV-vis spectrophotometry. Solubility enhancement of CoL3 complexes in SC-CO2 was accomplished by adding PhOH. The
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