Skip to Content
MilliporeSigma
All Photos(2)

Documents

141437

Sigma-Aldrich

4,7-Dichloroquinoline

≥99%

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C9H5Cl2N
CAS Number:
86-98-6
Molecular Weight:
198.05
Beilstein/REAXYS Number:
125359
EC Number:
201-714-7
MDL number:
MFCD00006774
UNSPSC Code:
12352100
PubChem Substance ID:
24848499
NACRES:
NA.22

assay

≥99%

form

solid

mp

81-83 °C (lit.)

solubility

chloroform: soluble 50 mg/mL, clear, colorless to greenish-yellow

SMILES string

Clc1ccc2c(Cl)ccnc2c1

InChI

1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H

InChI key

HXEWMTXDBOQQKO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

4,7-Dichloroquinoline was used in the synthesis of piperaquine. It was used as starting reagent in the synthesis of {3-amino-5-[(7-chloro-4-quinolyl)amino]phenyl}methanol.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

N Lindegårdh et al.
Journal of chromatography. A, 1135(2), 166-169 (2006-10-19)
A significant contaminant of the antimalarial drug piperaquine (1,3-bis-[4-(7-chloroquinolyl-4)-piperazinyl-1]propane) has been identified using liquid chromatography-mass spectrometry (LC-MS) and 2D NMR spectroscopy (1H-1H COSY, 1H-13C HSQC, 1H-13C HMBC). The impurity was identified as the positional isomer 1-[(5-chloroquinolin-4)-piperazinyl]-3-[(7-chloroquinolin-4)-piperazinyl]propane. The impurity is formed
J T Mague et al.
Acta crystallographica. Section C, Crystal structure communications, 51 ( Pt 7), 1423-1425 (1995-07-15)
The title compound C14H12C12N2O, has been shown to have an E configuration about the double bond in the propenal moiety. Significant delocalization of the lone pair on the N atom of the dimethylamino group into the pi system of this
S Delarue et al.
Chemical & pharmaceutical bulletin, 49(8), 933-937 (2001-08-23)
Amodiaquine (AQ) is an antimalarial which is effective against chloroquino-resistant strains of Plasmodium falciparum but whose clinical use is severely restricted because of associated hepatotoxicity and agranulocytosis. "One-pot" synthesis of formamidines likely to be transformed into AQ derivatives is reported.
Allergic contact dermatitis from 4,7-dichloroquinoline.
F C Pickering et al.
Contact dermatitis, 8(4), 269-270 (1982-07-01)
Howaida I Abd-Alla et al.
Natural product research, 23(11), 1035-1049 (2009-06-13)
The chemical constituents and biological activities of leaves and roots of Aloe hijazensis, collected in Saudi Arabia, are reported here for the first time. Twenty-two compounds were obtained, among them eight hydroxyquinones: aloe-emodin (1), emodin (2), chrysophanol (3), aloesaponarin II
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service