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123943

Sigma-Aldrich

Bis(4-nitrophenyl) phosphate

99%

Synonym(s):

Di-4-nitrophenyl hydrogenphosphate

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$63.49
5 G
$178.00
10 G
$285.00

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1 G
$63.49
5 G
$178.00
10 G
$285.00

About This Item

Linear Formula:
(O2NC6H4O)2P(O)OH
CAS Number:
Molecular Weight:
340.18
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$63.49

List Price$90.70Save 30%

In StockDetails


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Quality Level

assay

99%

form

solid

mp

172-175 °C (lit.)

functional group

nitro
phosphate

SMILES string

OP(=O)(Oc1ccc(cc1)[N+]([O-])=O)Oc2ccc(cc2)[N+]([O-])=O

InChI

1S/C12H9N2O8P/c15-13(16)9-1-5-11(6-2-9)21-23(19,20)22-12-7-3-10(4-8-12)14(17)18/h1-8H,(H,19,20)

InChI key

MHSVUSZEHNVFKW-UHFFFAOYSA-N

Application

Bis(4-nitrophenyl) phosphate(BNPP) has been used as substrate to determine the enzyme activity of root phosphodiesterases of wetland plants[1]. BNPP has been used to study the mechanism of cleavage of BNPP using oxamido-bridged dinuclear copper(II) complexes as catalysts[2].

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Skull and crossbones

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Danger

hcodes

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Eliska Rejmánková et al.
The New phytologist, 190(4), 968-976 (2011-06-30)
Phosphorus (P)-limited plants produce higher amounts of root phosphatases, but research has mostly focused on phosphomonoesterases (PMEs). Because phosphate diesters can form a significant proportion of organic P in wetlands, we aimed to determine whether wetland plants produce both root
M P Lim et al.
Cell death & disease, 2, e170-e170 (2011-06-10)
The major cellular event in the development and progression of liver fibrosis is the activation of hepatic stellate cells (HSCs). Activated HSCs proliferate and produce excess collagen, leading to accumulation of scar matrix and fibrotic liver. As such, the induction
Studies on the reaction kinetics and the mechanism of hydrolysis of bis (4-nitrophenyl) phosphate (BNPP) catalyzed by oxamido-bridged dinuclear copper (II) complexes in micellar solution.
Xie J, et al.
Transition Met. Chem. (London), 28(7), 782-787 (2003)
Wael M Abdel-Mageed et al.
Plants (Basel, Switzerland), 10(1) (2021-01-13)
A new lupane caffeoyl ester, lup-20(29)-ene 3β-caffeate-30-al (7), and a new oleanane-type triterpene, 3β-hydroxyolean-13(18)-en-12-one (17), were isolated from the aerial parts of Dobera glabra (Forssk), along with ten known triterpenes, including seven lupane-type lupeol (1), 30-nor-lup-3β-ol-20-one (2), ∆1-lupenone (3), lup-20(29)-en-3β,30-diol
Sarah Schmitz et al.
Molecular biotechnology, 62(1), 67-78 (2019-11-22)
Non-specific nuclease (NSN) can be applied in industrial downstream processing to remove nucleic acids from crude protein extracts or in cell-sorting systems to degrade nucleic acids derived from lysed cells. PsNuc from the ice-nucleating bacterium Pseudomonas syringae has the ability

Questions

  1. Could you please assist me with selecting a general esterase inhibitor? My application involves a compound that is not stable in plasma and the instability can be caused by esterase.

    1 answer
    1. A potential product of interest for inhibiting plasma esterase enzyme activity to maintain the stability of substances susceptible to esterase degradation is the product Bis(4-nitrophenyl) phosphate (123943).

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