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Key Documents

115452

Sigma-Aldrich

4-Fluoro-2-nitrobenzoic acid

≥90%

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About This Item

Linear Formula:
FC6H3(NO2)CO2H
CAS Number:
Molecular Weight:
185.11
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

≥90%

mp

140-145 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1ccc(F)cc1[N+]([O-])=O

InChI

1S/C7H4FNO4/c8-4-1-2-5(7(10)11)6(3-4)9(12)13/h1-3H,(H,10,11)

InChI key

YLUCXHMYRQUERW-UHFFFAOYSA-N

Application

4-Fluoro-2-nitrobenzoic acid has been used to study the reactions of substituted pyridines with the salicyl phosphate dianion.

Biochem/physiol Actions

4-Fluoro-2-nitrobenzoic acid enhances the binding of insulin to adipocytes.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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P E Phillips et al.
The Journal of biological chemistry, 263(23), 11175-11182 (1988-08-15)
Insulin binding to isolated rat white adipocytes at 15 degrees C, a temperature at which cellular degradation of insulin is negligible, has been found to be described by the Two-step Binding Model: R + I in equilibrium RI in equilibrium
Intramolecular general acid catalysis of phosphate monoester hydrolysis. The hydrolysis of salicyl phosphate.
J. Chem. Soc. Perkin Trans. II, 2, 149-155 (1972)

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