02615

(Ethoxycarbonylmethyl)triphenylphosphonium chloride

technical, ≥90% (AT)

• Synonym(s): (2-Ethoxy-2-oxoethyl)triphenylphosphonium chloride
• Linear Formula: CH₃CH₂OCOCH₂P(Cl)(C₆H₅)₃
• CAS Number: 17577-28-5
• Molecular Weight: 384.84
• Beilstein/REAXYS Number: 3924139
• EC Number: 241-548-2
• MDL number: MFCD00011746
• UNSPSC Code: 12352108
• PubChem Substance ID: 24845340
• NACRES: NA.22

Properties

• grade: technical
• assay: ≥90% (AT)
• reaction suitability: reaction type: C-C Bond Formation
• mp: 120-123 °C (dec.); 120-123 °C (lit.)
• functional group: ester; phosphine
• storage temp.: 2-8°C
• SMILES string: [Cl-].CCOC(=O)C[P+](c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C22H22O2P.ClH/c1-2-24-22(23)18-25(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21;/h3-17H,2,18H2,1H3;1H/q+1;/p-1
• InChI key: DJGHVEPNEJKZBF-UHFFFAOYSA-M

Description

Application

Reactant for:

• Preparation of disubstituted tetrahydrofurans as selective serotonin re-uptake inhibitors for the treatment of depression
• Ring-opening reactions with Wittig reagents
• Enantioselective total synthesis of the phytotoxic lactone herbarumin III via Keck′s asymmetric allylation and Sharpless epoxidation
• Synthesis of fluorobenzofurans via microwave-assisted tandem intramolecular Wittig and Claisen rearrangement reactions
• Preparation of phosphonium derivatives of coumarin

Other Notes

Starting material for preparing the Wittig-reagent

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves