V900691
Nicotinic hydrazide
Vetec™, reagent grade, 97%
Synonym(s):
Nicotinic acid hydrazide
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About This Item
Empirical Formula (Hill Notation):
C6H7N3O
CAS Number:
Molecular Weight:
137.14
Beilstein/REAXYS Number:
119299
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
grade
reagent grade
product line
Vetec™
assay
97%
mp
159-161 °C (lit.)
SMILES string
NNC(=O)c1cccnc1
InChI
1S/C6H7N3O/c7-9-6(10)5-2-1-3-8-4-5/h1-4H,7H2,(H,9,10)
InChI key
KFUSANSHCADHNJ-UHFFFAOYSA-N
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Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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N L Wengenack et al.
Biochemistry, 40(30), 8990-8996 (2001-07-27)
The antitubercular agent isoniazid can be activated by Mycobacterium tuberculosis KatG using either a peroxidase compound I/II or a superoxide-dependent oxyferrous pathway. The identity of activated isoniazid is unknown, but it has been suggested that it may be a free
Nives Galić et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 107, 263-270 (2013-02-26)
Structural forms of aroylhydrazones derived from nicotinic acid hydrazide have been studied in the solid state by FT-IR spectroscopy and in solution by NMR, UV-Vis and ATR spectroscopy. The studied compounds were N'-benzylidene-3-pyridinecarbohydrazide (1), N'-(2,4-dihydroxyphenylmethylidene)-3-pyridinecarbohydrazide (2), N'-(5-chloro-2-hydroxyphenylmethylidene)-3-pyridinecarbohydrazide (3), and N'-(3,5-dichloro-2-hydroxymethoxyphenylmethylidene)-3-pyridinecarbohydrazide
B J van der Walt et al.
The International journal of biochemistry, 26(9), 1081-1093 (1994-09-01)
1. Superoxide was generated during the auto-oxidation of the antituberculous drug, isonicotinic acid hydrazide (INH), but not with its meta-isomer, nicotinic acid hydrazide (NH). During Fe(3+)-stimulated oxidation of INH and NH, aromatic hydroxylation occurred which was inhibited by the chelating
B Toth
Oncology, 38(2), 106-109 (1981-01-01)
Nicotinic acid hydrazide was administered as a 0.125% solution in drinking water continuously for life from 6 weeks of age to randomly bred Swiss albino mice. As a result of treatment, the lung tumor incidence rose from 25 to 76%
Alireza Moradi et al.
Archiv der Pharmazie, 343(9), 509-518 (2010-09-02)
A series of 2-phenoxynicotinic acid hydrazides were synthesized and evaluated for their analgesic and anti-inflammatory activities. Several compounds having an unsubstituted phenyl/4-pyridyl or C-4 methoxy substituent on the terminal phenyl ring showed moderate to high analgesic or anti-inflammatory activity in
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