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V900576

Sigma-Aldrich

1,8-Dihydroxyanthraquinone

Vetec, reagent grade, 96%

Synonym(s):

Chrysazine, Danthron

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About This Item

Empirical Formula (Hill Notation):
C14H8O4
CAS Number:
Molecular Weight:
240.21
Beilstein/REAXYS Number:
2054727
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Pricing and availability is not currently available.

grade

reagent grade

product line

Vetec

assay

96%

mp

191-193 °C (lit.)

SMILES string

Oc1cccc2C(=O)c3cccc(O)c3C(=O)c12

InChI

1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16H

InChI key

QBPFLULOKWLNNW-UHFFFAOYSA-N

Gene Information

human ... RXRA(6256)

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Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

No data available

flash_point_c

No data available


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Chin-Chung Lin et al.
Oncology reports, 22(5), 1033-1037 (2009-09-30)
In this study, we investigated the effect of danthron on the cell migration and invasion of human brain glioblastoma multiforme GBM 8401 cells in vitro. The changes of migration and invasion of GBM 8401 cells after treatment with danthron were
Yu Wang et al.
Talanta, 94, 172-177 (2012-05-23)
1,8-Dihydroxyanthraquinone (DHAQ) can form an inclusion complex with β-cyclodextrin(β-CD) in aqueous media, which can be employed to solubilize and stabilize the DHAQ in water. With the assistance of ammonia, the supramolecular DHAQ-β-CD complex showed a selective chromogenic behavior toward Cu(2+)
Leena Laitinen et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 66(1), 135-145 (2006-11-14)
Interactions between widely used anthranoid laxatives and other simultaneously administered drugs are not known. In this paper, the influence of rhein, danthron, sennidins A/B, sennosides A/B, and senna leaf infusion was investigated on the permeability of furosemide, ketoprofen, paracetamol, propranolol
Yang Pan et al.
The journal of physical chemistry. A, 112(43), 10977-10984 (2008-10-03)
The photoionization and dissociative photoionization mechanism of 1,8-dihydroxyanthraquinone (1,8-DHAQ) have been investigated by infrared laser desorption/tunable synchrotron vacuum ultraviolet photoionization mass spectrometry (IR LD/VUV PIMS) technique and theoretical calculations. Consecutive losses of two carbon monoxides and elimination of hydroxyl group
Hsu-Feng Lu et al.
Neurochemical research, 35(7), 1105-1110 (2010-04-07)
Our primary studies had shown that danthron induced cytotoxic effects, including apoptosis and inhibition of migration and invasion. However, danthron-affected DNA damage and repair gene expressions are not clear. In this study, we investigated to examine whether or not danthron

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