1727009

Zolmitriptan

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): (4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone, (S)-4-((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)-2-oxazolidinone, 311C90
• Empirical Formula (Hill Notation): C₁₆H₂₁N₃O₂
• CAS Number: 139264-17-8
• Molecular Weight: 287.36
• MDL number: MFCD00871503
• UNSPSC Code: 41116107
• PubChem Substance ID: 329751294
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: zolmitriptan
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 15-25°C
• SMILES string: CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12
• InChI: 1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1
• InChI key: ULSDMUVEXKOYBU-ZDUSSCGKSA-N
• Gene Information: human ... HTR1B(3351) , HTR1D(3352)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Zolmitriptan USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Zolmitriptan Nasal Spray
• Zolmitriptan Orally Disintegrating Tablets
• Zolmitriptan Tablets

Biochem/physiol Actions

Zolmitriptan is a selective serotonin receptor agonist of the 5HT1B and 5HT1D subtypes, both centrally and peripherally. It has been used clinically for the acute treatment of migraine attacks with or without aura and cluster headaches.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable