Reactions of bisulfide and polysulfides with alachlor, propachlor, and metolachlor were examined in aqueous solution to investigate the role reduced sulfur species could play in effecting abiotic transformations of chloroacetanilide herbicides. Experiments at 25 degrees C demonstrated that reactions were
Molecular cancer therapeutics, 11(6), 1320-1331 (2012-04-12)
PI3K/AKT/mTOR pathway plays a key role in the tumorigenesis of many human cancers including prostate cancer. However, inhibitors of this pathway, such as Rad001, have not shown therapeutic efficacy as a single agent. Through a high-throughput screen of 5,000 widely
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 47(6), 1051-1057 (2009-05-09)
Alachlor and butachlor are chloracetanilide herbicides that induce olfactory tumors in rats, whereas propachlor does not. The mechanism by which alachlor induces tumors is distinct from many other nasal carcinogens, in that alachlor induces a gradual de-differentiation of the olfactory
Water science and technology : a journal of the International Association on Water Pollution Research, 55(3), 37-44 (2007-04-07)
Pesticide losses to the environment are unwanted due to possible environmental and health hazards. An experimental wetland is established to study the efficiency with respect to retention of sediments, nutrients and pesticides. Pesticides were applied on an arable soil plot
Xenobiotica; the fate of foreign compounds in biological systems, 24(10), 1003-1012 (1994-10-01)
1. 14C-labelled propachlor, alachlor, butachlor, metolachlor, methoxypropachlor and some of their mercapturic acid pathway metabolites (MAP) were given to rat either by gavage or by perfusion into a renal artery. MAP metabolites were isolated from bile and urine. 2. Rat
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.