Journal of chromatography. A, 1218(52), 9397-9405 (2011-11-29)
The performance of four commercially available cellulose tris(3,5-dimethylphenylcarbamate) based chiral stationary phases (CSPs) was evaluated with parallel high performance liquid chromatography (HPLC) and super critical fluid chromatography (SFC). Retention, enantioselectivity, resolution and efficiency were compared for a set of neutral
The Petasis reaction of 6-hydroxy adducts of 1-alkyl-2,3-dicyano-5-arylpyrazinium salts with trans-styrylboronic acids proved to proceed smoothly at room temperature to give the corresponding 5-(hetero)aryl-6-styryl substituted 1,6-dihydropyrazine derivatives. Also it has been found that C(6) unsubstituted 1,6-dihydro- or 1,4,5,6-tetrahydropyrazine derivatives can
Development of a sensitive and rapid method for quantitation of (S)-(-)- and (R)-(+)-metoprolol in human plasma by chiral LC?ESI?MS/MS
Sharma, Primal, et al.
Journal of Pharmaceutical Analysis, 4 (1), 63-79 (2014)
Evaluating dynamic kinetic resolution strategies in the asymmetric hydrosilylation of cyclic ketimines
The chiral separation of 10 beta-adrenergic blockers (acebutalol, alprenolol, bufuralol, bisoprolol, celiprolol, carazolol, indenolol, metoprolol, oxprenolol and propranolol) was achieved on CelluCoat column (250 mm x 4.6mm, 5 microm particle size). The mobile phases used were (90:10:0.2, v/v/v) and (95:5:0.2
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