821887

TOYOPEARL^® Phenyl-600 HIC Bulk Media

bottle of 25 mL, phase phenyl, 65 μm particle size

• UNSPSC Code: 41115700

Properties

• product line: TOYOPEARL^®
• form: slurry
• packaging: bottle of 25 mL
• manufacturer/tradename: Tosoh 21887
• parameter: ≤50% organic solvent; 3 bar max. pressure
• technique(s): LPLC: suitable
• matrix: hydroxylated methacrylic polymer
• matrix active group: phenyl phase
• particle size: 65 μm
• operating pH: 1-13
• capacity: 55 g/L±10 adsorption capacity (lysozyme)
• separation technique: hydrophobic interaction (HIC)

Description

General description

Toyopearl Phenyl-600 resin has the middle hydrophobicity of the five HIC ligands offered by Tosoh Bioscience. Its pore size has been optimized for the chromatography of monoclonal antibodies and it is typically used in an intermediate or polishing step. It is a very high recovery and high dynamic capacity resin for both large and small proteins. When used as the polishing step up to an extra 5% yield may be seen compared to other Phenyl resins. To see other products optimized for HIC purification of mAbs please see Toyopearl PPG-600 and Toyopearl Butyl-600 resins.

Specifications

Clean in place with 0.5 M NaOH or 0.1 M HCl.

Physical form

72% (v/v) slurry in 20% (v/v) ethanol

Shipped in 20% (v/v) ethanol.

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Legal Information

Toyopearl is a registered trademark of Tosoh Corporation

Safety Information

• pictograms: GHS02
• signalword: Danger
• hcodes: H225
• pcodes: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3