TSKgel® CN-80Ts HPLC column is comprised of cyanopropyl groups bonded to the silica† and finds applications in reversed-phase high performance liquid chromatographic technique. It is an alternative to C18 (ODS) and C8 (Octyl) phases. The cyano group is the least hydrophobic of the 100 Å phases available and in some cases is used under normal phase conditions. The chromatograms below show retention and selectivity of TSKgel® CN-80Ts for 3 aromatic hydrocarbon compounds. Bonded phase pore size is indicated by the number in the product description, in this case TSKgel® CN-80Ts has 80 Å nominal pore size. The pore size of the base silica is 100 Å. CN-80Ts is useful for the analysis of polar peptides, amino acids, and other pharmaceutical and food & beverage products. As with other 80Ts products, TSKgel® CN-80Ts provides reproducible separations of molecules below 6,000 MW.
Physical form
Shipped in 60% acetonitrile - 40% water.
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TSKgel is a registered trademark of Tosoh Corporation
Peptide separation in normal-phase liquid chromatography: study of selectivity and mobile phase effects on various columns.
Yoshida T and Okada T
Journal of Chromatography A, 840(1), 1-9 (1999)
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