SUPELCOSIL LC-DB phases are specially deactivated for basic compounds. These columns provide shorter retention, better peak shape, and higher efficiency for organic bases than can be obtained on other Type A silica reversed-phase columns.
Application
SUPELCOSIL LC-18-DB HPLC Column has been used for the separation of:
Analytes of pharmaceutical relevance during their analysis using LC in conjunction with principal component analysis (PCA).[1]
Uracil in aqueous solutions during its separation by reversed phase high performance liquid chromatography equipped with ultraviolet-visible (UV-Vis) detection.[2]
Recommended products
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Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Characterisation of reversed-phase liquid chromatographic columns by chromatographic tests. Evaluation of 36 test parameters: repeatability, reproducibility and correlation.
Visky D, et al.
Journal of Chromatography A, 977(1), 39-58 (2002)
Chromatographic classification and comparison of commercially available reversed-phase liquid chromatographic columns using principal component analysis
Euerby MR and Petersson P
Journal of Chromatography A, 994(1-2), 13-36 (2003)
American journal of physiology. Gastrointestinal and liver physiology, 320(3), G380-G395 (2021-01-28)
Pancreatic ductal adenocarcinoma (PDAC) is highly metastatic and represents one of the deadliest forms of human cancers. Previous studies showed that activation of Yes-associated protein 1 (YAP1) plays a key role in malignant transformation in the pancreas. In this study
Journal of chromatography. B, Biomedical sciences and applications, 755(1-2), 331-335 (2001-06-08)
A HPLC-UV determination of loratadine in human plasma is presented. After simple liquid-liquid extraction with 2-methylbutane-hexane (2:1) and evaporation of organic phase the compounds were re-dissolved in 0.01 M HCl, evaporated again and finally separated on a Supelcosil LC-18-DB column.
A rapid, isocratic method for the determination of tryptophan in Escherichia coli fermentation broths by reversed-phase HPLC is described. Tryptophan can be measured in fermentations containing either chemically defined media or media with hydrolyzed protein supplements. The procedure was rugged
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