Applied and environmental microbiology, 78(15), 5313-5319 (2012-05-29)
O-Demethylation of insecticide methoxychlor is well known as a phase I metabolic reaction in various eukaryotic organisms. Regarding prokaryotic organisms, however, no individual species involved in such reaction have been specified and characterized so far. Here we successfully isolated a
Journal of toxicology and environmental health. Part B, Critical reviews, 14(5-7), 413-422 (2011-07-28)
Assessing potential risk associated with exposure to endocrine-disrupting chemicals (EDC) has been difficult due to species specific variation in vulnerability and to both short- and long-term effects produced by EDC. In precocial birds, embryonic exposure to EDC impacts sexual differentiation
Critical reviews in toxicology, 27(4), 367-379 (1997-07-01)
Estrogens can have a variety of physiological effects, especially on the reproductive system. Chemicals with estrogenic activity that are present in the environment may thus be considered potentially hazardous to development and/or reproduction. Methoxychlor is one such chemical, a chlorinated
Immunosuppressive environmental chemicals may increase the potency of allergens and thereby play a role in the development of allergic diseases such as allergic rhinitis, asthma and atopic dermatitis (AD). This study's primary objective was to examine the mechanisms behind the
International journal of molecular medicine, 29(5), 883-890 (2012-02-07)
Various endocrine disrupting chemicals (EDCs) are exogenous compounds found in the environment and have the potential to interfere with the endocrine system and hormonal regulation. Among EDCs, bisphenol A (BPA) and 1,1,1-trichloro-2,2-bis(4-methoxyphenol)-ethane [methoxychlor (MXC)] have estrogenic activity resulting in a variety
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