48520-U

Chloroform

analytical standard

• Synonym(s): Methylidyne trichloride, Trichloromethane
• Empirical Formula (Hill Notation): CHCl₃
• CAS Number: 67-66-3
• Molecular Weight: 119.38
• Beilstein/REAXYS Number: 1731042
• EC Number: 200-663-8
• MDL number: MFCD00000826
• UNSPSC Code: 77101502
• PubChem Substance ID: 329757381
• NACRES: NA.24

Properties

• grade: analytical standard
• vapor density: 4.1 (vs air)
• vapor pressure: 160 mmHg ( 20 °C)
• assay: ≥99.8%
• CofA: current certificate can be downloaded
• packaging: ampule of 1000 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• color: colorless
• refractive index: n20/D 1.445 (lit.)
• bp: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• density: 1.492 g/mL at 25 °C (lit.)
• application(s): agriculture; environmental
• format: neat
• storage temp.: 2-30°C
• SMILES string: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• InChI key: HEDRZPFGACZZDS-UHFFFAOYSA-N

Description

General description

Chloroform is widely used as an industrial solvent, aerosol propellant and as a preservative in concentrations between 0.1 and 0.5 percent in aqueous pharmaceutical preparations. It is a human carcinogen with cardiotoxic and hepatotoxic effects and is also known to cause skin infections.[1][2]

Application

Chloroform may be used as an analytical standard for the determination of the analyte in aqueous pharmaceutical formulations[2] by chromatography and drinking water samples[3] by spectrofluorimetry.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash
• ppe: Eyeshields, Faceshields, Gloves