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Supelco

D-Biotin

analytical standard

Synonym(s):

Biotin, D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H

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About This Item

Empirical Formula (Hill Notation):
C10H16N2O3S
CAS Number:
Molecular Weight:
244.31
Beilstein/REAXYS Number:
86838
EC Number:
MDL number:
UNSPSC Code:
12164500
PubChem Substance ID:

grade

analytical standard

feature

standard type water soluble vitamin

packaging

ampule of 100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

231-233 °C (lit.)

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

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General description

D-biotin is water soluble vitamin, which belongs to the B-complex group of vitamins. It generally serves as a covalently-bound coenzyme for several carboxylases. It is an essential micronutrient required for normal cell functions and can be obtained both dietary sources as well as gut microbiota.

Application

D-Biotin may be used as an analytical reference standard for the quantification of the analyte in food samples using high-performance liquid chromatography (HPLC)/avidin-binding assay.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Pharmacological Effects of Biotin in Animals
L R-N and C F-M
Mini-Reviews in Medicinal Chemistry, 17, 529-529 (2017)
Determination of the biotin content of select foods using accurate and sensitive HPLC/avidin binding
Staggs GC, et al.
Journal of food composition and analysis, 17(6), 767-776 (2004)
Lipopolysaccharide inhibits colonic biotin uptake via interference with membrane expression of its transporter: a role for a casein kinase 2-mediated pathway
Lakhan R and Said.MS
American Journal of Physiology. Cell Physiology, 312, C376-C384 (2017)
Tuan V Bui et al.
Neuron, 78(1), 191-204 (2013-04-16)
Accurate motor performance depends on the integration in spinal microcircuits of sensory feedback information. Hand grasp is a skilled motor behavior known to require cutaneous sensory feedback, but spinal microcircuits that process and relay this feedback to the motor system
Naruo Nikoh et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(28), 10257-10262 (2014-07-02)
Obligate insect-bacterium nutritional mutualism is among the most sophisticated forms of symbiosis, wherein the host and the symbiont are integrated into a coherent biological entity and unable to survive without the partnership. Originally, however, such obligate symbiotic bacteria must have

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