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Supelco

Fluorescamine

pkg of 100 mL

Synonym(s):

Supelco® TLC Spray Reagents

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About This Item

EC Number:
UNSPSC Code:
41116105

description

Fluorescamine

form

liquid

packaging

pkg of 100 mL

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General description

Fluorescamine is a reagent generally used for the detection of primary amines in the picomole range. It reacts instantaneously with amines, when it is in aqueous media and at room temperature. The products formed are highly fluorescent, though the reagent and its degradation products are non-fluorescent.[1] It is also a novel reagent, used for the detection of amino acids, amines, peptides and proteins. It is highly sensitive and group specific, thereby making it useful, during histochemistry.[2]

Application

Fluorescamine spray was used to visualize polypeptides, in an investigation done to identify the chemical nature of human tumor antigen (OFA-I-1).[3] It was also used to label nucleotides, in an experimental study, conducted to detect end stage renal disease (ESRD), using spectrofluorometer.[4]

Legal Information

Supelco is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Fluorescamine: A novel reagent for the histochemical detection of amino groups.
Hakanson R
Histochemistry, 39 (1), 15-23 (1974)
Labeling of nucleosides with fluorescamine and detection by spectrofluorometer for End Stage Renal Disease.
Saudi Journal of Biological Sciences, 20 (4), 327-331 (2013)
Fluorescamine: a reagent for assay of amino acids, peptides, proteins, and primary amines in the picomole range.
Udenfriend S
Science, 178 (4063), 871-872 (1972)
Ganglioside GM2 as a human tumor antigen (OFA-I-1).
tadashi T
Proceedings of the National Academy of Sciences of the USA, 80 (17), 5392-5396 (1983)
Jeremy N Moore et al.
Archives of environmental contamination and toxicology, 57(2), 416-425 (2009-05-22)
Dose- and time-dependent effects of environmentally relevant concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEQ) of 2,3,7,8-tetrachlorodibenzofuran (TCDF), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF), or a mixture of these two congeners on hepatic P450 enzyme activity and tissue morphology, including jaw histology, of adult ranch mink were

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