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Key Documents

33149-U

Supelco

BSTFA + TMCS, 99:1

Synonym(s):

Chlorotrimethylsilane, N,O-Bis(trimethylsilyl)trifluoroacetamide, Trimethylchlorosilane, Trimethylsilyl chloride

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About This Item

UNSPSC Code:
12352200

description

(SYLON BFT)

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

packaging

pkg of 1 × 50 mL

concentration

(BSTFA + TMCS, 99:1)

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General description

BSTFA is a stronger silylating reagent as compared to BSA. In most cases, BSTFA is used in place of BSA as the reaction products are more volatile avoiding interference with early peaks in a chromatogram. BSTFA along with TMCS is considered to be a suitable reagent for quantitative reactions.[1]

Application

It was used in the derivatization of water during determination of trace levels of bisphenol A from plastic water containers, using solid-phase microextraction (SPME) coupled with GC-MS.[2]
Suitable for the derivitazation of alkylphosphonic acids and aminoalkylphosphonic acids, aminothiols, bilirubins, carboxylic acids sodium salts, glycerophospholipids, homovanillic acids and vanillylmandelic acid , 3-O-methyldopamine and 4-O-methyldopamine, phosphoryl and phosphono ethanolamine, polyphosphoinositides, steroid phosphates, tryptamines, tyrosine, tryptophan and metabolites.

Other Notes

Reagent for isothiocyanate (amino compounds), oxime, trimethylsilyl (TMS), trimethylsilyl deacylated polyphosphoinositides and trimethylsilyl glycerophosphate esters.

pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

75.2 °F - closed cup

flash_point_c

24 °C - closed cup


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N. Narasimhachari
Journal of Chromatography A, 9, 502-502 (1971)
D.R. Knapp
Handbook of Analytical Derivatization Reactions, 214-215 (1979)
A.J. Poole et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 73, 517-517 (1976)
P.W. Albro and L. Fishbein
Journal of Chromatography A, 55, 297-297 (1971)
Combined gas chromatography-mass spectrometry of brain polyphosphoinositides.
T J Cicero et al.
Biochemical and biophysical research communications, 42(3), 428-433 (1971-02-05)

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