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33039

Supelco

HMDS+TMCS+Pyridine, 3:1:9 (Sylon™ HTP)

pkg of 25 mL

Synonym(s):

Chlorotrimethylsilane, Hexamethyldisilazane, Trimethylchlorosilane, Trimethylsilyl chloride, 1,1,1,3,3,3–Hexamethyldisilane+Τrimethylchlorosilane+Pyridine, Sylon™ HTP

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About This Item

UNSPSC Code:
41116105

grade

derivatization grade ((GC derivatization))

description

3:1:9 (SYLON HTP)

composition

1,1,3,3,3-Hexamethyldisilazane, 22.9%
Pyridine, 69.4%
Trimethylchlorosilane, 7.7 % (w/v)

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

packaging

pkg of 25 mL

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Application

HMDS+TMCS+Pyridine in the ratio of 3:1:9 may be used as the silylating agent, during multi-targeted profiling of the major phytohormones by gas chromatography-mass spectrometry (GC-MS).[1] This reagent was used as a derivatizing agent during sample processing during determination of 5-hydroxymethylfurfural in wood using GC-MS method.[2]

Legal Information

Sylon is a trademark of Sigma-Aldrich Co. LLC
Sylon CT is a trademark of Sigma-Aldrich Co. LLC

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

68.0 °F - closed cup

flash_point_c

20 °C - closed cup

ppe

Faceshields, Gloves, Goggles

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Certificates of Analysis (COA)

Lot/Batch Number
LC26998V
LC24359V
LC23660V
LC22602V
LC22427V

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Development of a GC-MS method for 5-hydroxymethylfurfural determination in wood after steam-explosion pretreatment.
Senila, Lacrimioara, et al.
Revista de Chimie (Bucharest, Romania), 63, 559-563 (2012)
Studies on sphingosines. 10. Use of trimethylsilyl ethers for the gas chromatography and mass spectrometry sphingosines.
K A Karlsson
Acta chemica Scandinavica, 19(10), 2425-2427 (1965-01-01)
Claudia Birkemeyer et al.
Journal of chromatography. A, 993(1-2), 89-102 (2003-05-09)
In the present investigation we report selection of the N-methyl-N-(tert.-butydimethylsilyl)trifluoroacetamide (MTBSTFA) reagent as the most comprehensive derivatization protocol among 17 tested reactions covering trifluoroacetylation, pentafluorobenzylation, methylations, and trimethylsilylations. MTBSTFA allowed easy and robust tert.-butyldimethylsilyl derivatization of 1-aminocyclopropane-1-carboxylic acid, indole-3-acetic acid
A gas chromatographic procedure for the simultaneous determination of pyridoxine, ascorbic acid, and nicotinamide in vitamin capsules and tablets.
L T Sennello et al.
Analytical chemistry, 41(1), 171-173 (1969-01-01)
The measurement of myo-inositol, myo-inosose-2 and scyllo-inositol in mammalian tissues.
W R Sherman et al.
Biochimica et biophysica acta, 158(2), 197-205 (1968-05-01)
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