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33014

Supelco

Chlorotrimethylsilane

pkg of 100 mL

Synonym(s):

TMCS, Derivatization Grade, TMCS, Trimethylchlorosilane, Trimethylsilyl chloride

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About This Item

EC Number:
200-900-5
UNSPSC Code:
41116105

grade

derivatization grade ((GC derivatization))
derivatization grade

description

Silylation reagent

form

liquid

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations
reagent type: derivatization reagent
reaction type: Silylations

packaging

pkg of 100 mL

technique(s)

GC/MS: suitable

General description

Chlorotrimethylsilane is widely used in characterising organolithium compounds. It is also used in establishing the degree of polymetallation by organolithium compounds.[1]

Application

It was used to reconstitute the phytic acid residue during derivatization procedure, before injecting the residue into GC for determination of phytic acid content in biological samples.[2] It was also used in toluene for silanizing all the glassware used for detecting, identifying and quantifying polychlorinated biphenyls (PCB) using solid-phase microextraction combined with gas chromatography with electron capture detection.[3]

Other Notes

Reagent for trimethylsilyl chlorohydrin, trimethylsilyl and trimethylsilyl ether.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A

supp_hazards

EUH014

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

-18.4 °F - closed cup

flash_point_c

-28 °C - closed cup

ppe

Faceshields, Gloves, Goggles

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Certificates of Analysis (COA)

Lot/Batch Number
LC25441V
LC15748V
LC09001V
LB99925
LB54957

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D.R. Knapp
Handbook of Analytical Derivatization Reactions, 472-472 (1979)
Cláudia H Kowalski et al.
Talanta, 116, 315-321 (2013-10-24)
Due to the tendency of polychlorinated biphenyls (PCB) to accumulate in matrixes with high lipid content, the contamination of the breast milk with these compounds is a serious issue, mainly to the newborn. In this study, milk samples were collected
Jszafranek et al.
Journal of Chromatography A, 88, 149-149 (1974)
B. J. Wakefield
The Chemistry of Organolithium Compounds, 260-260 (2013)
M.G.Horning et al.
Journal of Gas Chromatography, 5, 297-297 (1967)
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