00380

Glutaric semialdehyde

≥85.0% (GC)

• Synonym(s): 5-Oxopentanoic acid, 5-Oxovaleric acid, Glutaraldehydic acid, Glutaric acid semialdehyde
• Empirical Formula (Hill Notation): C₅H₈O₃
• CAS Number: 5746-02-1
• Molecular Weight: 116.12
• Beilstein/REAXYS Number: 1747012
• MDL number: MFCD00057569
• UNSPSC Code: 41116107
• PubChem Substance ID: 329747055
• NACRES: NA.24

Properties

• assay: ≥85.0% (GC)
• format: neat
• storage temp.: −20°C
• SMILES string: [H]C(CCCC(O)=O)=O
• InChI: 1S/C5H8O3/c6-4-2-1-3-5(7)8/h4H,1-3H2,(H,7,8)
• InChI key: VBKPPDYGFUZOAJ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Metabolite of lysine degradation. In the lysine degradation IV pathway, glutarate semialdehyde reacts with NADP+ and H2O to produce glutarate, NADPH, and H+. In this pathway, glutarate semialdehyde is produced by the reaction between 5-aminopentanoate and 2-ketoglutarate, with L-glutamate as a byproduct. The enzyme responsible for this reaction is 5-aminovalerate aminotransferase. In the lysine degradation III pathway, glutarate semialdehyde reacts with NAD+ and H2O to produce glutarate and NADH. In this pathway, glutarate semialdehyde is produced by the reaction between 5-aminopentanoate and 2-ketoglutarate, with L-glutamate as a byproduct. The enzyme responsible for this reaction is 5-aminovalerate aminotransferase.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable