SML1631

Cefodizime Sodium

≥96% (HPLC)

• Synonym(s): 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazoly)(methoxyimino)acetyl}-3-[[[5-(carboxymethyl)-4-methyl-2-thiazilyl]-8-oxo-, sodium salt (1:2), (6R,7R)-
• Empirical Formula (Hill Notation): C₂₀H₁₈N₆O₇S₄ · 2Na
• CAS Number: 86329-79-5
• Molecular Weight: 628.63
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825515

Properties

• biological source: synthetic
• assay: ≥96% (HPLC)
• form: powder
• solubility: H₂O: soluble 270 mg/mL
• storage temp.: 2-8°C
• SMILES string: O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N\OC)=O)[C@]3([H])N1C(C([O-])=O)=C(CSC4=NC(C)=C(CC([O-])=O)S4)CC3
• InChI: 1S/C20H20N6O7S4.2Na/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9;;/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32);;/q;2*+1/p-2/b25-12-;;/t13-,17-;;/m1../s1
• InChI key: WBOBLQIRACJNPA-AEKYOGSZSA-L

Description

Biochem/physiol Actions

Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime was demonstrated to be effective against upper and lower respiratory tract infections, urinary tract infections, and gonorrhea. Cefodizime regulates the cytokines expression of neutrophils through toll-like receptor 4 (TLR-4) stimulated by Klebsiella pneumonie.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable