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Z731358

Vaccine Adjuvants and Delivery Systems

M Singh, John Wiley and sons, 2007, 449 pp., hard cover

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About This Item

ISBN-13:
978-0-471-73907-4
UNSPSC Code:
55101509

publication info

M Singh, John Wiley and sons, 2007, 449 pp., hard cover

manufacturer/tradename

Wiley

General description

This unique resource brings scientists up to date on recent advances and provides the information they need to select candidate adjuvants. Written by leading experts, this book provides a comprehensive overview of the rapidly evolving field and developing formulation methods and covers cutting-edge technologies and gives the current status of adjuvants in clinical trials and those still in the pre-clinical stage.

It includes detailed information on specific vaccine adjuvants, including MF59, TLR4 agonists, new iscoms, cytokines, polyphosphazenes, and more. The text discusses the mechanisms of adjuvant actions, and covers some novel adjuvants and delivery systems and the safety evaluation of adjuvants.

Table of Contents

Chapter 1. Development of vaccine adjuvants - a historical perspective
Chapter 2. Antigen-Processing and Presentation
Chapter 3. Mechanisms of Adjuvant Action .
Chapter 4. Aluminum-containing Adjuvants: Properties, Formulation and Use
Chapter 5. MF59: A Safe and Potent Oil in Water Emulsion Adjuvant
Chapter 6. TLR4 agonists as vaccine adjuvants .
Chapter 7. Immunostimulatory CpG Oligodeoxynucleotides as Vaccine Adjuvants .
Chapter 8. Small Molecule Immunopotentiators as Vaccine Adjuvants
Chapter 9. New ISCOMs Meet Unsettled Vaccine Demands .
Chapter 10. Surface Charged Poly(lactide-co-glycolide) Microparticles as Novel Antigen Delivery Systems
Chapter 11. Liposomal Cytokines and Liposomes Targeted to Costimulatory Molecules as Adjuvants for HIV Subunit Vaccines
Chapter 12. Archaeosomes Vaccine Adjuvants for Cross-priming CD8+ T Cell Immunity .
Chapter 13 Mucosal Adjuvants and Delivery Systems
Chapter 14. Cytokines as Vaccine Adjuvants
Chapter 15. Polyphosphazenes as vaccine adjuvants
Chapter 16. Vaccine Delivery by Transdermal Electroporation
Chapter 17. Nonclinical Safety Assessment of Vaccines, and the Evaluation of Novel Adjuvants and Delivery Systems
Chapter 18. Safety Evaluation of Vaccine Adjuvants

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