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Z730343

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Biology of Cancer

three decades of recent cancer research

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About This Item

ISBN-13:
978-0815340768
UNSPSC Code:
55101509

publication info

R. Weinberg, Garland Science, 2007, 864 pp., soft cover/CD-ROM

manufacturer/tradename

Garland

General description

The Biology of Cancer synthesizes the findings of three decades of recent cancer research and proposes a conceptual framework from which to teach about these discoveries. It provides the necessary structure, organization, and content for a course on cancer biology for advanced undergraduates and beginning doctoral students.

The book is comprehensive and offers many pedagogical features to assist teaching and learning. The text provides current information on topics such as tumor stem cells and recently introduced chemotherapeutics. State-of-the-art techniques are discussed throughout. Modern biomedical research is explored, helping readers to hone their analytical abilities and to assimilate and think clearly about complex biological processes.

Table of Contents

Contents:
1. The Biology and Genetics of Cells and Organisms
2. The Nature of Cancer
3. Tumor Viruses
4. Cellular Oncogenes
5. Growth Factors and their Receptors
6. Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer
7. Tumor Suppressor Genes
8. pRb and Control of the Cell Cycle Clock
9. p53 and Apoptosis: Master Guardian and Executioner
10. Eternal Life: Cell Immortalization and Tumorigenesis
11. Multistep Tumorigenesis
12. Maintenance of Genomic Integrity and the Development of Cancer
13. Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis
14. Moving Out: Invasion and Metastasis
15. Crowd Control: Tumor Immunology and Immunotherapy
16. The Rational Treatment of Cancer

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