X6000

Xylometazoline hydrochloride

Name: Xylometazoline hydrochloride
Brand: SIGMA
Price: 148 USD

Synonym(s):

2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₂₄N₂ · HCl

CAS Number:

1218-35-5

Molecular Weight:

280.84

NACRES:

NA.77

PubChem Substance ID:

24278781

UNSPSC Code:

41116107

EC Number:

214-936-4

MDL number:

MFCD00238707

Quality level:

200

Key Documents

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Quality Level

200

originator

Novartis

SMILES string

CC1=CC(C(C)(C)C)=CC(C)=C1CC2=NCCN2.Cl

InChI

1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H

InChI key

YGWFCQYETHJKNX-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

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This Item	O2378	A9899	X0100000
Sigma-Aldrich X6000 Xylometazoline hydrochloride	Sigma-Aldrich O2378 Oxymetazoline hydrochloride	Sigma-Aldrich A9899 Antazoline hydrochloride	X0100000 Xylometazoline hydrochloride
Quality Level 200	Quality Level 100	Quality Level 200	Quality Level -
originator Novartis	originator Schering Plough	originator Novartis	originator -
Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)	Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), HTR1A(3350), HTR1B(3351), HTR1D(3352)	Gene Information human ... HRH1(3269)	Gene Information -

Biochem/physiol Actions

α-adrenoceptor agonist; imidazoline binding site ligand.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Preparation of nose for nasal endoscopy: cotton pledget packing versus topical spray. A prospective randomized blinded study.

Prasun Mishra et al.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 270(1), 117-121 (2012-03-20)

During nasal endoscopy it is essential to have proper visualization of structures with minimal discomfort to patient and surgeon. For this it is essential that the nose is well prepared before the procedure. The main objective of the study is

Xylometazoline abuse induced ischemic stroke in a young adult.

Daniela Leupold et al.

The neurologist, 17(1), 41-43 (2010-12-31)

substance abuse is an important cause of ischemic stroke in the young. This includes over-the-counter dietary supplements and cough and cold remedies, which were reported to be an independent risk factor for hemorrhagic stroke. this article describes a young male

Nasal inspiratory flow: at rest and sniffing.

Catherine E Rennie et al.

International forum of allergy & rhinology, 1(2), 128-135 (2012-01-31)

This study quantifies the time-varying flow rate during inspiration at rest and in sniffing, both predecongestion and postdecongestion. It aims to provide a better understanding of nasal airflow mechanics, for application to the physiological modeling of nasal respiration and to

[Nasal drops addiction--the case report].

Katarzyna Korzeniowska et al.

Przeglad lekarski, 69(10), 1168-1169 (2013-02-21)

The article describes the case of 34-years old man, who has used nasal drops with xylomethazoline for three years. Health consequence of uncontrolled use of the drops and treatment were prescribed. Described problem confirms the need of physicians and pharmacists

[Misuse of substances theoretically without abuse potential--case series].

Jacek Sein Anand et al.

Przeglad lekarski, 66(6), 290-292 (2009-10-01)

The aim of our study was to present cases of misuse of different substances theoretically without abuse potential. In the last few years such behavior became an increasing problem in toxicological and emergency units. Lack of typical signs of intoxication

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Global Trade Item Number

SKU	GTIN
X6000-5G	04061837549830
X6000-25G	04061837549816

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