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Key Documents

UC287

Sigma-Aldrich

7α-Hydroxytestosterone

Synonym(s):

4-Androstene-7α,17β-diol-3-one, 7α,17β-Dihydroxyandrost-4-en-3-one

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About This Item

Empirical Formula (Hill Notation):
C19H28O3
Molecular Weight:
304.42
UNSPSC Code:
12161501
NACRES:
NA.77

form

solid

drug control

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

color

white

mp

218-220 °C

storage temp.

2-8°C

Biochem/physiol Actions

7α-Hydroxytestosterone is known to block the synthesis of dihydrotestosterone and 5α-androstane-3α, 17β-diol in mature rat testis[1].
CYP2A1 (rat) metabolite; androgenic

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H351,H360

Hazard Classifications

Carc. 2 - Repr. 1B

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
119K3350
107K3259
066K3252
117K3250

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P A Rosness et al.
Biochimica et biophysica acta, 488(1), 55-68 (1977-07-20)
1. Testicular 7 alpha-hydroxylation of testerone was assayed in cell extracts of rats between 12 and 79 days of age. Maximal 7 alpha-hydroxylase activity was observed about 60 days, while insignificant activity was obtained prior to 42 days of age.

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