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TRUEPEG

Sigma-Aldrich

TrueGel3D Crosslinker

PEG non cell-degradable crosslinker

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About This Item

UNSPSC Code:
12352207
NACRES:
NA.71

shipped in

dry ice

storage temp.

−20°C

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General description

PEG-Link is comprised of polyethylene glycol and thiol (SH) groups at each end. The thiol groups form stable thioether bond with thiol-reactive groups of the polymers (Mal-PVA, Mal-Dextran, SG-PVA and SG-Dextran), which results in stable hydrogel. The matrix metalloproteases secreted by cells cannot cleave PEG crosslinker.

Application

TRUEPEG is used to crosslink PVA and dextran polymers to generate stable hydrogel.

Features and Benefits

Non-MMP degradable.

Components

TRUEPEG contains PEG non cell-degradable crosslinker lyophilized and water.

Caution

Avoid prolong exposure of PEG non cell-degradable crosslinker to air.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3


Certificates of Analysis (COA)

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Articles

Troubleshoot TrueGel3D™ hydrogel formation and cell viability issues with RGD-degradable polymer and CD cell-degradable crosslinker.

TrueGel3D™ is a synthetic hydrogels platform for 3D cell culture that aim to mimic the natural extracellular environment for more physiological culture conditions

Protocols

TrueGel3D™ is a chemically defined hydrogel for 3D cell growth, facilitating microchannel filling with slow gelation.

TrueGel3D hydrogel enables cell encapsulation for 3D culture, mimicking native tissue environment with chemically defined properties.

An advanced protocol is available for TrueGel 3D kits for 3D cell culture for peptides concentration or stiffness optimisation

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