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Key Documents

T9306

Sigma-Aldrich

Tag-72 antigen from human fluids

buffered aqueous solution

Synonym(s):

Cancer-associated Ca-72-4

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About This Item

MDL number:
UNSPSC Code:
12352202

biological source

human fluids

form

buffered aqueous solution

shipped in

dry ice

Storage temp.

−20°C

Biochem/physiol Actions

Expression of TAG-72 was shown to be induced by interferon α treatment in patients with colorectal cancer. [1]

Quality

Partially purified

Unit Definition

One unit is an arbitrary amount related to a reference antigen preparation using CIS-RIA method.

Physical form

Solution in 0.15 M phosphate buffered saline, pH 7.4, containing 0.1% sodium azide.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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V G Johnson et al.
Cancer research, 46(2), 850-857 (1986-02-01)
Monoclonal antibody B72.3 binds a high-molecular-weight tumor-associated glycoprotein identified as TAG-72. This study reports the partial purification and characterization of TAG-72 from a xenograft of a human carcinoma cell line, LS-174T, which expresses high levels of this antigen. The tumor
D M Mahvi et al.
Cancer immunology, immunotherapy : CII, 40(5), 311-314 (1995-05-01)
Interferons up-regulate the expression of human tumor-associated antigens in animal models and in vitro. The use of interferons may enhance the immunodetection and immunotherapy of tumors by monoclonal antibodies that detect tumor antigens. For this strategy to be effective, however
A E Evans et al.
Cancer, 38(2), 661-666 (1976-08-01)
A randomized study was designed to determine the effect of intermittent oral cyclophosphamide on the rate of metastases in children with localized and regional neuroblastoma. Secondary objectives of the study were to determine the value of the proposed staging system

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