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Key Documents

T3569

Sigma-Aldrich

Monoclonal Anti-Triadin antibody produced in mouse

clone IIG12, ascites fluid

Synonym(s):

Anti-CARDAR, Anti-CPVT5, Anti-TDN, Anti-TRISK

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

IIG12, monoclonal

mol wt

antigen 95 kDa

species reactivity

rabbit, mouse

technique(s)

immunohistochemistry: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

mouse ... Trdn(76757)

Immunogen

rabbit skeletal muscle triads

Physical form

Solution of ascites fluid diluted in phosphate buffered saline containing 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids


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Vanilla Martina Vecchi et al.
International journal of molecular sciences, 22(18) (2021-09-29)
Different forms of sudden cardiac death have been described, including a recently identified form of genetic arrhythmogenic disorder, named "Triadin KnockOut Syndrome" (TKOS). TKOS is associated with recessive mutations in the TRDN gene, encoding for TRIADIN, but the pathogenic mechanism
Laura L Smith et al.
Human molecular genetics, 23(13), 3566-3578 (2014-02-20)
Autosomal recessive centronuclear myopathy (CNM2), caused by mutations in bridging integrator 1 (BIN1), is a mildly progressive neuromuscular disorder characterized by abnormally centralized myonuclei and muscle weakness. BIN1 is important for membrane sensing and remodeling in vitro in different cell

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