T2830

Tomatine hydrate

≥95% (HPLC)

• Synonym(s): Lycopersicin, NSC 234440, NSC 9223, Spirosolane, a-Tomatine, alpha-tomatine, b-D-galactopyranoside deriv
• Empirical Formula (Hill Notation): C₅₀H₈₃NO₂₁ · xH₂O
• CAS Number: 17406-45-0
• Molecular Weight: 1034.19 (anhydrous basis)
• EC Number: 241-429-5
• UNSPSC Code: 12352200

Properties

• assay: ≥95% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: >20 mg/mL
• storage temp.: room temp

Description

Application

Tomatine has been used as a standard for HPLC-based determination of tomatine from red and green tomatoes¹. It has also been used to study its teratogenic effect using frog embryos².

Biochem/physiol Actions

When the pure compounds were isolated, alpha-Tomatine was highly effective in inhibiting all of the cell lines, whereas dehydrotomatine, tomatidenol, and tomatidine had little, if any, effect on cell inhibition. It had been previously shown that commercial tomatine, which is customarily an approximate 10:1 mixture of α-tomatine and dehydrotomatine, strongly inhibits the growth of both colon and liver cancer cells.

It had been previously shown that commercial tomatine, which is customarily an approximate 10:1 mixture of α-tomatine and dehydrotomatine, strongly inhibits the growth of both colon and liver cancer cells.

Preparation Note

Tomatine hydrate is soluble in DMSO at a concentration that is greater than 20 mg/ml.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable