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T0656

Sigma-Aldrich

1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril

Synonym(s):

Iodo-Gen®, NSC 4462

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250 MG
$296.00

$296.00

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250 MG
$296.00

About This Item

Empirical Formula (Hill Notation):
C16H10Cl4N4O2
CAS Number:
51592-06-4
Molecular Weight:
432.09
MDL number:
MFCD00027367
UNSPSC Code:
12352101
PubChem Substance ID:
24899904
NACRES:
NA.22

$296.00

Available to ship onApril 29, 2025Details

Request a Bulk Order

storage temp.

2-8°C

Quality Level

100

SMILES string

ClN1C(=O)N(Cl)C2(N(Cl)C(=O)N(Cl)C12c3ccccc3)c4ccccc4

InChI

1S/C16H10Cl4N4O2/c17-21-13(25)23(19)16(12-9-5-2-6-10-12)15(21,11-7-3-1-4-8-11)22(18)14(26)24(16)20/h1-10H

InChI key

FJQZXCPWAGYPSD-UHFFFAOYSA-N

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Related Categories

Application

Iodination reagent used in radioiodination acting as an oxidative agent

Reagent involved in comparison studies with chloramine-T

Reagent used for oxidation of urazoles

Legal Information

Iodo-Gen is a registered trademark of Pierce Biotechnology, Inc.

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Exclamation mark
GHS07

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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000213687
0000203102
13170612
079M4098V

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P K Garg et al.
Bioconjugate chemistry, 7(2), 233-239 (1996-03-01)
Two peptides of potential utility for targeting melanoma cells, alpha-melanocyte-stimulating hormone (alpha-MSH) and its more potent analogue [Nle4,D-Phe7]-alpha-MSH, were radioiodinated in 45-65% yield using N-succinimidyl 3-[125I]iodobenzoate (SIB). To determine whether this labeling method resulted in improved in vitro and in
M R Zalutsky et al.
Nuclear medicine and biology, 26(7), 781-790 (2000-01-11)
Monoclonal antibody (MAb) internalization can have a major effect on tumor retention of radiolabel. Two anti-HER-2/neu MAbs (TA1 and 520C9) were radioiodinated using the iodogen, N-succinimidyl 5-iodo-3-pyridinecarboxylate (SIPC), and tyramine-cellobiose (TCB) methods. Paired-label studies compared internalization and cellular processing of
P K Garg et al.
Bioconjugate chemistry, 6(4), 493-501 (1995-07-01)
The F(ab')2 fragment of monoclonal antibody (MAb) Me1-14 was labeled with 125I using the Iodogen method and by reaction with N-succinimidyl 3-[125I]iodobenzoate (SIB). The labeled catabolites generated after exposure to tissue homogenates in vitro and following administration of labeled F(ab')2
Helge Wiig et al.
The Journal of physiology, 567(Pt 2), 557-567 (2005-07-05)
Knowledge of macromolecular distribution volumes is essential in understanding fluid transport within normal and pathological tissues. In this study in vivo we determined the distribution volumes of several macromolecules, including one monoclonal antibody, in tumours and tested whether charges associated
E Carnazzi et al.
Journal of medicinal chemistry, 37(12), 1841-1849 (1994-06-10)
A series of new linear photoactivatable and iodinatable antagonists of the neuropeptidic hormone vasopressin was designed and synthesized by a combination of PyBOP-mediated Boc/solid-phase peptide synthesis and solution synthesis approaches. These were based on modifications of a previously reported potent
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