T0266

Sodium tauroursodeoxycholate

• Synonym(s): 3α,7β-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide, Tauroursodeoxycholic acid sodium salt
• Linear Formula: C₂₆H₄₄NO₆SNa
• CAS Number: 35807-85-3
• Molecular Weight: 521.69
• MDL number: MFCD00065451
• UNSPSC Code: 12161900
• PubChem Substance ID: 24899875
• NACRES: NA.25

Properties

• description: anionic
• Quality Level: 200
• assay: ≥95.0% (TLC)
• mol wt: 521.69 g/mol
• CMC: 4
• HLB: 20.1
• SMILES string: [H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(NCCS(=O)([O-])=O)=O.[Na+]
• InChI: 1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-/m1/s1
• InChI key: BHTRKEVKTKCXOH-LBSADWJPSA-N

Description

General description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

Application

Sodium tauroursodeoxycholate has been used in a study to assess whether ER stress is involved in palmitic acid upregulation (PA). It has also been used in a study to investigate its effect on Estradiol-17β-D-glucuronide (E-17G) induced cholestasis in female rats.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• ppe: Eyeshields, Gloves, type N95 (US)