SRP6533

RBP4 from mouse

recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)

• Synonym(s): PRBP, Plasma retinol-binding protein, RBP, Retinol Binding Protein 4
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: mouse
• recombinant: expressed in HEK 293 cells
• assay: ≥90% (SDS-PAGE)
• form: liquid
• mol wt: monomer ~230 kDa (Mouse RBP4 aa 19-201 is fused at the N-terminus to a FLAG0174-tag.)
• packaging: pkg of 10 μg; pkg of 50 μg
• impurities: <0.1 EU/μg endotoxin (LAL test)
• UniProt accession no.: Q00724
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... RBP4(19662)

Description

General description

Retinol binding protein 4 (RBP4; RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

Physical form

0.2 μm-filtered solution in PBS, pH 7.2.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable