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SRP6520

Sigma-Aldrich

Ubiquitin-Biotinylated (all lysines unmodified)

≥90% (SDS-PAGE)

Synonym(s):

CEP80, HUBCEP80, RPS27A, Ribosomal Protein S27a, UBA80, UBB, UBCEP1, UBCEP80

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

assay

≥90% (SDS-PAGE)

form

liquid

mol wt

9.106 kDa

packaging

pkg of 50 μg

concentration

8 mg/mL

shipped in

dry ice

storage temp.

−70°C

General description

Post-translational modification of proteins by ubiquitin (Ub) is a key regulatory process that impacts almost all cellular functions. Ubiquitylation occurs through isopeptide linkage between the C-terminus of Ub and the ε-amino group of a lysine (Lys) residue on the target substrate. Ub itself has seven Lys residues (6, 11, 27, 29, 33, 48, and 63), any of which can participate in further ubiquitylation, generating polyUb chains. Thebiotinylated ubiquitin carries a single biotin molecule attached at a defined location and unlike other biotinylated ubiquitins, avoids modification of the N-terminus, C-terminus or any of the seven Lys side chains. Therefore, this biotinylated ubiquitin has all lysines available for conjugation and can be incorporated into polyubiquitin chains of any linkage type.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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