SRP6452

IL20RB/IL-20R2 human

recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)

• Synonym(s): DIRS1, FNDC6, IL-20R-beta
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in HEK 293 cells
• assay: ≥90% (SDS-PAGE)
• form: lyophilized
• mol wt: calculated mol wt 49.1 kDa (This protein fused with Fc fragment of human IgG1 at the C-terminus.); observed mol wt 50 kDa (DTT reduced. 100 kDa non reduced. Asp 30 is the predicted N-terminal.)
• packaging: pkg of 10 and 50 μg
• impurities: <1 EU/μg endotoxin (LAL test)
• UniProt accession no.: Q6UXL0
• shipped in: wet ice
• Storage temp.: −20°C
• Gene Information: human ... IL20RB(53833)

Description

General description

Interleukin-20 receptor subunit β (IL20RB) is also known as IL-20R2, DIRS1, which belongs to the type II cytokine receptor family. IL20RB / IL-20R2 contains two fibronectin type-III domains. IL20RB / IL-20R2 is widely expressed with highest levels in skin and testis. IL20RB can be fused with IL20RA or IL22RA1 forming heterodimer. The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.

Physical form

Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH 7.0. Normally Mannitol or Trehalose is added as protectants before lyophilization.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable