SRP6379

CD87 human

recombinant, expressed in HEK 293 cells, ≥92% (SDS-PAGE)

• Synonym(s): CD87, MO3
• UNSPSC Code: 12352200

Properties

• biological source: human
• recombinant: expressed in HEK 293 cells
• tag: 6-His tagged (C-terminus)
• assay: ≥92% (SDS-PAGE)
• form: lyophilized
• mol wt: calculated mol wt 32.1 kDa; observed mol wt 44-48 kDa (DTT-reduced. Protein migrates due to glycosylation. Leu 23 is the predicted N-terminus.)
• packaging: pkg of 20 and 100 μg
• UniProt accession no.: Q03405
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... PLAUR(5329)

Description

General description

Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR act as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.

Physical form

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable