SRP6364

KLRC2 human

recombinant, expressed in E. coli, ≥85% (SDS-PAGE)

• Synonym(s): CD159c, NKG2-C, NKG2-C type II integral membrane protein, NKG2C
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥85% (SDS-PAGE)
• form: liquid
• mol wt: 18.4 kDa (162 aa, 94-231 aa + His Tag)
• packaging: pkg of 50 μg
• concentration: 0.5 mg/mL
• UniProt accession no.: P26717
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... KLRC2(3822)

Description

General description

NKG2-C type II integral membrane protein, also known as KLRC2, plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. Recombinant human KLRC2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Physical form

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable