SRP6351

CD244 human

recombinant, expressed in E. coli, ≥85% (SDS-PAGE)

• Synonym(s): 2B4, CD244 molecule, NAIL, NKR2B4, Nmrk, SLAMF4, natural killer cell receptor 2B4
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥85% (SDS-PAGE)
• form: liquid
• mol wt: 25.5 kDa (230 aa, 19-224 aa + His Tag)
• packaging: pkg of 50 μg
• concentration: 0.5 mg/mL
• UniProt accession no.: Q9BZW8
• shipped in: dry ice
• Storage temp.: −70°C
• Gene Information: human ... CD244(51744)

Description

General description

CD244 (Natural Killer Cell Receptor 2B4), also known as Cluster of Differentiation 244, contains 2 Ig-like (immunoglobulin-like) domains. A role for the subtypes of CD2 Ig superfamily receptors has been recently demonstrated in eosinophilic inflammation in experimental asthma and atopic asthmatics. Functions of CD244 molecules are in eosinophil adhesion and chemotaxis, and correlated the results to the pathophysiology of allergic rhinitis (AR). The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Recombinant human CD244 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Physical form

0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea. .

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable