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Key Documents

SRP6151

Sigma-Aldrich

UBE2H human

≥95% (SDS-PAGE)

Synonym(s):

GID3, UbcH2, Ubiquitin carrier protein H, Ubiquitin-conjugating enzyme E2 H, Ubiquitin-conjugating enzyme E2-20K, Ubiquitin-protein ligase H

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About This Item

UNSPSC Code:
12352200

biological source

human

assay

≥95% (SDS-PAGE)

form

liquid

mol wt

21.649 kDa (His Tagged)

packaging

pkg of 3 nmol

NCBI accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... UBE2H(7328)

General description

Ubiquitin-conjugating enzyme E2 H (UBE2H) is a member of the ubiquitin-conjugating enzyme family. Protein modification with ubiquitin is a vital cellular apparatus for directing abnormal or short-lived proteins for degradation. Ubiquitination requires at least 3 classes of enzymes: ubiquitin-activating enzymes (E1s) ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2H receives ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. UBE2H protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and Zebrafish homologs.

Physical form

75 μL of a 40 μM solution (3 nmoles) in 20 mM Tris, pH 7.4, 150 mM NaCl, 10 mM DTT and 10% glycerol.

Preparation Note

Centrifuge the vial prior to opening.

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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