SRP6102

FKBP14 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Synonym(s): 22 kDa FK506-binding protein, FK506-binding protein 14, FKBP22, PPIase FKBP14, Peptidyl prolyl cis-trans isomerase FKBP14
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥90% (SDS-PAGE)
• form: liquid
• mol wt: 24.2 kDa (213 aa, 20-211 aa + NT His Tag)
• packaging: pkg of 100 μg
• NCBI accession no.: Q9NWM8
• UniProt accession no.: Q9NWM8
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... FKBP14(55033)

Description

General description

FKBP14 enzyme accelerates the folding of proteins during protein synthesis. It contains 2 EF-hand domains and one PPIase FKBP-type domain. Truncation of the amino-terminus of FKBP14 significantly decreases peptidyl prolyl cis-trans isomerase activity, therefore suggesting that the PPIase FKBP-type domain must be located at the N-terminus.

Physical form

1 mg/mL solution in PBS (pH 7.4) containing 10% glycerol.

Preparation Note

Centrifuge the vial prior to opening.

Other Notes

MGSSHHHHHH SSGLVPRGSH MALIPEPEVK IEVLQKPFIC HRKTKGGDLM LVHYEGYLEK DGSLFHSTHK HNNGQPIWFT LGILEALKGW DQGLKGMCVG EKRKLIIPPA LGYGKEGKGK IPPESTLIFN IDLLEIRNGP RSHESFQEMD LNDDWKLSKD EVKAYLKKEF EKHGAVVNES HHDALVEDIF DKEDEDKDGF ISAREFTYKH DEL

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable