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Key Documents

SRP6072

Sigma-Aldrich

PPIL1 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Synonym(s):

CGI-124, CYPL1, PPIase, Peptidyl prolyl cis-trans isomerase-like 1, Rotamase PPIL1

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

liquid

mol wt

19.3 kDa

packaging

pkg of 100 μg

NCBI accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PPIL1(51645)

General description

Peptidylprolyl isomerase (cyclophilin)-like 1, also known as PPIL1, is a member of peptidyl-propyl cis trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. Human PPIL1 might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. So it can be developed as a novel molecular target for colon-cancer therapy.

Physical form

1 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol.

Preparation Note

Centrifuge the vial prior to opening.

Other Notes

MAAIPPDSWQ PPNVYLETSM GIIVLELYWK HAPKTCKNFA ELARRGYYNG TKFHRIIKDF MIQGGDPTGT GRGGASIYGK QFEDELHPDL KFTGAGILAM ANAGPDTNGS QFFVTLAPTQ WLDGKHTIFG RVCQGIGMVN RVGMVETNSQ DRPVDDVKII KAYPSGLEHH HHHH

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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