SRP6034
LBP from mouse
recombinant, expressed in CHO cells, ≥95% (SDS-PAGE)
Synonym(s):
Lipopolysaccharide binding protein
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About This Item
biological source
mouse
recombinant
expressed in CHO cells
assay
≥95% (SDS-PAGE)
form
lyophilized
mol wt
64.0 kDa
packaging
pkg of 10 μg
impurities
Endotoxin, tested
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... LBP(218846)
General description
Natural LBP is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNF?). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
Physical form
Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in 10 μl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Fang Chen et al.
ChemMedChem, 14(15), 1457-1465 (2019-07-11)
Antimicrobial peptides (AMPs) that are able to neutralize toxins are promising antibiotics. In this study we investigated the role of structurally conserved amino acids in reduced human defensin 5 (HD5RED ), which is an endogenous peptide with antibacterial action and the
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