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Key Documents

SRP6029

Sigma-Aldrich

Isopeptidase T (long form) human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Synonym(s):

Isoopeptidase T, Isopeptidase T (long form), IsopeptidaseT, USP5, Ubiquitin-specific protease 5

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

liquid

mol wt

97.0 kDa

packaging

pkg of 25 μg

concentration

~2.0 mg/mL

impurities

Endotoxin, tested

NCBI accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... UBP5(8078)

General description

Isopeptidase T is a ubiquitin-specific processing protease (UBP) that specifically disassembles free K48-linked polyubiquitin chains into ubiquitin monomers. There are two human isopeptidase T isoforms; Isopeptidase T short form (isoT-S) and Isopeptidase T long form (isoT-L) which differ by an insertion of 23 amino acids in isoT-L. Isopeptidase T is the only UBP known to require zinc binding to be active.

Physical form

Supplied at a concentration of 2.0 mg/ml in 50 mM Tris, 10 Mmn ?-mercaptoethanol, pH 7.5.

pictograms

Environment

hcodes

pcodes

Hazard Classifications

Aquatic Chronic 2

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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