SRP5368
UHMK1 (KIS), GST tagged human
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
KIS, KIST, UHMK1
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20 μG
$372.00
$372.00
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20 μG
$372.00
About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
$372.00
Usually ships in 2 weeks.
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
~65 kDa
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... UHMK1(127933)
General description
UHMK1(KIS) or U2AF homology motif (UHM) kinase 1 is a serine/threonine protein kinase that promotes cell cycle progression through G1 phase. UHMK1 phosphorylates the cyclin-dependent kinase inhibitor 1B (p27Kip1) and this results in its export to the nucleus where it undergoes degradation. UHMK1 is a growth factor-dependent nuclear kinase which can regulate cell cycle progression. Elevated levels of UHMK1 protein in leukemia cells has been shown to promote cell cycle progression. UHMK1 has also been shown to function in the adult nervous system where it is highly expressed and the gene has been associated with schizophrenia.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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