SRP5201
KAT9, GST tagged human
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
FLJ10422
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
mol wt
~86 kDa
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... ELP3(55140)
General description
KAT9 (also known as ELP3) is the catalytic subunit of the histone acetyltransferase (HAT) elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons. The knockdown of KAT9 by antisense morpholinos in zebrafish embryos resulted in dose-dependent shortening and abnormal branching of motor neurons with no concomitant morphologic abnormalities. KAT9 knockdown also impairs paternal DNA demethylation as indicated by reporter binding, immunostaining, and bisulfite sequencing.
Physical form
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
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