SRP4631

RELM-alpha from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• Synonym(s): Cysteine-rich secreted protein A12-γ, Cysteine-rich secreted protein FIZZ1, Parasite-induced macrophage novel gene 1 protein, RELMα, RELM-a, Resistin-like α
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: mouse
• recombinant: expressed in E. coli
• assay: ≥98% (HPLC); ≥98% (SDS-PAGE)
• form: lyophilized
• mol wt: ~10.0 kDa
• packaging: pkg of 25 μg
• impurities: endotoxin, tested
• NCBI accession no.: Q9EP95
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... Retna(57262)

Description

General description

RELM-α belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-α and Resistin are secreted exclusively by adipocytes while RELM-β is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-α re still unknown. Recombinant mouse RELM-α is a 10.0 kDa monomeric protein containing 88 amino acid residues.

Physical form

Sterile filtered and lyophilized from 10 mM Tris, pH 7.5 plus 25 mM NaCl.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1 μg/ul. The solution can then be diluted into other aqueous buffers.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable