SRP4246
MIP-1α from rat
recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)
Synonym(s):
CCL3, G0/G1 switch regulatory protein 19-1, MIP-1-α, Macrophage inflammatory protein 1-α, Small inducible cytokine A3, Tonsillar lymphocyte LD78 α protein
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About This Item
biological source
rat
recombinant
expressed in E. coli
assay
≥95% (HPLC)
≥95% (SDS-PAGE)
form
lyophilized
mol wt
~7.8 kDa
packaging
pkg of 20 μg
impurities
endotoxin, tested
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... Ccl3(25542)
General description
Rat macrophage inflammatory protein-1α (MIP-1α) is an 8.0 kDa protein containing 69 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue microphages.
Physical form
Sterile filtered and then lyophilized without any additives.
Reconstitution
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1 mg/mL. This solution can then be diluted into other aqueous buffers.
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Katsuyuki Matsushita et al.
Anesthesiology, 120(6), 1491-1503 (2014-03-05)
The chemokine family has been revealed to be involved in the pathogenesis of neuropathic pain. In this study, the authors investigated the role of chemokine (C-C motif) ligand 3 and its receptors chemokine (C-C motif) receptor 1 and chemokine (C-C
Inger Øynebråten et al.
PloS one, 9(8), e104814-e104814 (2014-08-15)
DNA vaccines based on subunits from pathogens have several advantages over other vaccine strategies. DNA vaccines can easily be modified, they show good safety profiles, are stable and inexpensive to produce, and the immune response can be focused to the
Filip Bednar et al.
Journal of immunology (Baltimore, Md. : 1950), 192(11), 5305-5313 (2014-04-30)
The cross-regulation of G protein-coupled receptors (GPCRs) plays an important role in the immune response. Studies from several laboratories have suggested that a hierarchy of sensitivities to cross-desensitization exists for the chemoattractant GPCRs. We carried out experiments to study the
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