recombinant, expressed in E. coli, ≥99% (SDS-PAGE), ≥99% (HPLC)
Synonym(s):
CCL3, G0/G1 switch regulatory protein 19-1, MIP-1-α, Macrophage inflammatory protein 1-α, Small inducible cytokine A3, Tonsillar lymphocyte LD78 α protein
mouse macrophage inflammatory protein-1α (MIP-1α) is an 7.8 kDa protein containing 69 amino acid residues. It is part of the CC chemokine family and plays an important role in the inflammatory response of blood monocytes and tissue microphages.
Physical form
Sterile filtered and then lyophilized without any additives.
Reconstitution
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1 mg/mL. This solution can then be diluted into other aqueous buffers.
DNA vaccines based on subunits from pathogens have several advantages over other vaccine strategies. DNA vaccines can easily be modified, they show good safety profiles, are stable and inexpensive to produce, and the immune response can be focused to the
The chemokine family has been revealed to be involved in the pathogenesis of neuropathic pain. In this study, the authors investigated the role of chemokine (C-C motif) ligand 3 and its receptors chemokine (C-C motif) receptor 1 and chemokine (C-C
Journal of immunology (Baltimore, Md. : 1950), 195(2), 632-642 (2015-06-19)
Although classical dendritic cells (DCs) arise from distinct progenitors in the bone marrow, the origin of inflammatory DCs and the distinction between monocyte-derived DCs and macrophages is less clear. In vitro culture of mouse bone marrow cells with GM-CSF is
Journal of immunology (Baltimore, Md. : 1950), 192(11), 5305-5313 (2014-04-30)
The cross-regulation of G protein-coupled receptors (GPCRs) plays an important role in the immune response. Studies from several laboratories have suggested that a hierarchy of sensitivities to cross-desensitization exists for the chemoattractant GPCRs. We carried out experiments to study the
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