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SRP4176F

Sigma-Aldrich

IL-17F human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

Synonym(s):

IL17 A/F, IL17F, InterleukinF

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

assay

≥98% (HPLC)
≥98% (SDS-PAGE)

form

lyophilized

mol wt

~30.1 kDa

packaging

pkg of 25 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

endotoxin, tested

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL17F(112744)

General description

IL-17Fis a member of the IL-17 family of structurally-related cytokines. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F stimulates proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant human IL-17F is a 30.1 kDa cytokine consisting of two 134 amino acid polypeptide chains.

Physical form

Sterile filtered and lyophilized from PBS.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstituted in water to a concentration of 0.1-1.0 μg/μL. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Zhenhua Luo et al.
Inflammation, 38(3), 978-986 (2014-11-12)
The objective of this study was to investigate the expression level, clinical significance, and possible regulating role of IL-17F in patients of chronic periodontitis. Periodontal local tissues were obtained from chronic periodontitis (CP) and healthy controls (HC) for real-time PCR

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