IL-17Fis a member of the IL-17 family of structurally-related cytokines. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F stimulates proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant human IL-17F is a 30.1 kDa cytokine consisting of two 134 amino acid polypeptide chains.
Physical form
Sterile filtered and lyophilized from PBS.
Reconstitution
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstituted in water to a concentration of 0.1-1.0 μg/μL. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.
The objective of this study was to investigate the expression level, clinical significance, and possible regulating role of IL-17F in patients of chronic periodontitis. Periodontal local tissues were obtained from chronic periodontitis (CP) and healthy controls (HC) for real-time PCR
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